This research goals to research the position of miR-495 in neuronal cell apoptosis after acute spinal cord injury (ASCI). The ASCI rat mannequin was established and the Basso, Beattie, and Bresnahan (BBB) rating was assessed. miR-495, PR area containing 5 (PRDM5), and Bcl-2 expressions have been measured by qRT-PCR or western blotting. Neuronal cell line PC-12 was subjected to hypoxia situation to simulate the in vitro ASCI mannequin. PC-12 cell apoptosis was measured by movement cytometry, and the interplay between miR-495 and PRDM5 was confirmed by twin luciferase reporter assay.
Results confirmed that BBB rating was considerably decreased in ASCI rats in contrast with sham rats. miR-495 expression was down-regulated in spinal cord tissue of ASCI rats and hypoxia-induced PC-12 cells, and PRDM5 protein stage was up-regulated in spinal cord tissue of ASCI rats and hypoxia-induced PC-12 cells. miR-495 overexpression may cut back apoptosis of PC-12 cells, and up-regulated anti-apoptosis protein Bcl-2 protein stage.
Moreover, PRDM5 was a goal of miR-495, and mRNA and protein ranges of PRDM5 have been negatively regulated by miR-495. miR-495 overexpression may cut back the hypoxia-induced PC-12 cell apoptosis, whereas PRDM5 overexpression abolished this inhibiting impact. The agomir-495 was injected into ASCI rats, and Bcl-2 protein stage and BBB rating have been elevated, however the PRDM5 overexpression reversed these outcomes. Overall, we concluded that miR-495 may inhibit neuronal cell apoptosis and relieve acute spinal cord injury through inhibiting PRDM5.
Second-Order Orbital Optimization with Large Active Spaces Using Adaptive Sampling Configuration Interaction (ASCI) and Its Application to Molecular Geometry Optimization
First report of Erysiphe corylacearum, agent of powdery mildew, on hazelnut ( Corylus avellana) in Romania

TNN Antibody |
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| 1-CSB-PA775994 | Cusabio |
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Description: A polyclonal antibody against TNN. Recognizes TNN from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;ELISA:1:3000-1:10000, IHC:1:50-1:200 |
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TNN Antibody |
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| GWB-MW809H | GenWay Biotech | 50ug | Ask for price |
TNN Antibody |
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| E037267 | EnoGene | 100μg/100μl | 255 EUR |
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Description: Available in various conjugation types. |
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TNN Antibody |
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| E40PV3999 | EnoGene | 50ul | 395 EUR |
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Description: Available in various conjugation types. |
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TNN Antibody |
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| MBS7110555-005mg | MyBiosource | 0.05mg | 190 EUR |
TNN Antibody |
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| MBS7110555-01mg | MyBiosource | 0.1mg | 270 EUR |
TNN Antibody |
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| MBS7110555-5x01mg | MyBiosource | 5×0.1mg | 1205 EUR |
TNN Antibody |
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| MBS7128236-005mL | MyBiosource | 0.05mL | 190 EUR |
TNN Antibody |
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| MBS7128236-01mL | MyBiosource | 0.1mL | 270 EUR |
TNN Antibody |
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| MBS7128236-5x01mL | MyBiosource | 5×0.1mL | 1205 EUR |
TNN Antibody |
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| MBS7128237-005mL | MyBiosource | 0.05mL | 190 EUR |
TNN Antibody |
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| MBS7128237-01mL | MyBiosource | 0.1mL | 270 EUR |
TNN Antibody |
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| MBS7128237-5x01mL | MyBiosource | 5×0.1mL | 1205 EUR |
TNN Antibody |
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| MBS9401195-01mL | MyBiosource | 0.1mL | 305 EUR |
TNN Antibody |
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| MBS9401195-5x01mL | MyBiosource | 5×0.1mL | 1230 EUR |
TNN Antibody (Center) |
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| MBS9201489-008mL | MyBiosource | 0.08mL | 210 EUR |
TNN Antibody (Center) |
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| MBS9201489-04mL | MyBiosource | 0.4mL | 430 EUR |
TNN Antibody (Center) |
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| MBS9201489-5x04mL | MyBiosource | 5×0.4mL | 1910 EUR |
TNN Polyclonal Antibody |
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| E-AB-16087-120uL | Elabscience Biotech | 120uL | 240 EUR |
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Description: Unconjugated |
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TNN Polyclonal Antibody |
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| E-AB-16087-200uL | Elabscience Biotech | 200uL | 399 EUR |
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Description: Unconjugated |
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TNN Polyclonal Antibody |
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| E-AB-16087-20uL | Elabscience Biotech | 20uL | 73 EUR |
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Description: Unconjugated |
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TNN Polyclonal Antibody |
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| E-AB-16087-60uL | Elabscience Biotech | 60uL | 143 EUR |
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Description: Unconjugated |
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TNN Polyclonal Antibody |
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| E-AB-12897-120uL | Elabscience Biotech | 120uL | 240 EUR |
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Description: Unconjugated |
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TNN Polyclonal Antibody |
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| E-AB-12897-200uL | Elabscience Biotech | 200uL | 399 EUR |
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Description: Unconjugated |
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TNN Polyclonal Antibody |
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| E-AB-12897-20uL | Elabscience Biotech | 20uL | 73 EUR |
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Description: Unconjugated |
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TNN Polyclonal Antibody |
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| E-AB-12897-60uL | Elabscience Biotech | 60uL | 143 EUR |
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Description: Unconjugated |
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TNN Conjugated Antibody |
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| C37267 | SAB | 100ul | 476.4 EUR |
TNN Polyclonal Antibody |
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| MBS2521434-002mL | MyBiosource | 0.02mL | 135 EUR |
TNN Polyclonal Antibody |
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| MBS2521434-006mL | MyBiosource | 0.06mL | 190 EUR |
TNN Polyclonal Antibody |
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| MBS2521434-012mL | MyBiosource | 0.12mL | 265 EUR |
TNN Polyclonal Antibody |
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| MBS2521434-02mL | MyBiosource | 0.2mL | 415 EUR |
TNN Polyclonal Antibody |
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| MBS2521434-5x02mL | MyBiosource | 5×0.2mL | 1835 EUR |
TNN Polyclonal Antibody |
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| MBS2527133-002mL | MyBiosource | 0.02mL | 135 EUR |
TNN Polyclonal Antibody |
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| MBS2527133-006mL | MyBiosource | 0.06mL | 190 EUR |
TNN Polyclonal Antibody |
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| MBS2527133-012mL | MyBiosource | 0.12mL | 265 EUR |
TNN Polyclonal Antibody |
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| MBS2527133-02mL | MyBiosource | 0.2mL | 415 EUR |
TNN Polyclonal Antibody |
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| MBS2527133-5x02mL | MyBiosource | 5×0.2mL | 1835 EUR |
TNN Conjugated Antibody |
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| MBS9447710-01mLAF350 | MyBiosource | 0.1mL(AF350) | 480 EUR |
TNN Conjugated Antibody |
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| MBS9447710-01mLAF405 | MyBiosource | 0.1mL(AF405) | 480 EUR |
TNN Conjugated Antibody |
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| MBS9447710-01mLAF488 | MyBiosource | 0.1mL(AF488) | 480 EUR |
TNN Conjugated Antibody |
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| MBS9447710-01mLAF555 | MyBiosource | 0.1mL(AF555) | 480 EUR |
TNN Conjugated Antibody |
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| MBS9447710-01mLBiotin | MyBiosource | 0.1mL(Biotin) | 480 EUR |
TNN Polyclonal Antibody |
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| RD78781A-120uL | Reddot Biotech | 120μL | 360 EUR |
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Description: This protein is involved in neurite outgrowth and cell migration in hippocampal explants.It has three EGF-like domains, one fibrinogen C-terminal domain and nine fibronectin type III domains.Tenascins are extracellular matrix proteins present during the development of organisms as well as in pathological conditions.Tenascin-W, the fourth and last member of the tenascin family remains the least well-characterized one. |
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TNN Polyclonal Antibody |
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| RD78781A-200uL | Reddot Biotech | 200μL | 630 EUR |
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Description: This protein is involved in neurite outgrowth and cell migration in hippocampal explants.It has three EGF-like domains, one fibrinogen C-terminal domain and nine fibronectin type III domains.Tenascins are extracellular matrix proteins present during the development of organisms as well as in pathological conditions.Tenascin-W, the fourth and last member of the tenascin family remains the least well-characterized one. |
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TNN Polyclonal Antibody |
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| RD78781A-20uL | Reddot Biotech | 20μL | 109.5 EUR |
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Description: This protein is involved in neurite outgrowth and cell migration in hippocampal explants.It has three EGF-like domains, one fibrinogen C-terminal domain and nine fibronectin type III domains.Tenascins are extracellular matrix proteins present during the development of organisms as well as in pathological conditions.Tenascin-W, the fourth and last member of the tenascin family remains the least well-characterized one. |
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TNN Polyclonal Antibody |
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| RD78781A-60uL | Reddot Biotech | 60μL | 214.5 EUR |
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Description: This protein is involved in neurite outgrowth and cell migration in hippocampal explants.It has three EGF-like domains, one fibrinogen C-terminal domain and nine fibronectin type III domains.Tenascins are extracellular matrix proteins present during the development of organisms as well as in pathological conditions.Tenascin-W, the fourth and last member of the tenascin family remains the least well-characterized one. |
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TNN Polyclonal Antibody |
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| RD76582A-120uL | Reddot Biotech | 120μL | 360 EUR |
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Description: This protein is involved in neurite outgrowth and cell migration in hippocampal explants.It has three EGF-like domains, one fibrinogen C-terminal domain and nine fibronectin type III domains.Tenascins are extracellular matrix proteins present during the development of organisms as well as in pathological conditions.Tenascin-W, the fourth and last member of the tenascin family remains the least well-characterized one. |
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TNN Polyclonal Antibody |
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| RD76582A-200uL | Reddot Biotech | 200μL | 630 EUR |
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Description: This protein is involved in neurite outgrowth and cell migration in hippocampal explants.It has three EGF-like domains, one fibrinogen C-terminal domain and nine fibronectin type III domains.Tenascins are extracellular matrix proteins present during the development of organisms as well as in pathological conditions.Tenascin-W, the fourth and last member of the tenascin family remains the least well-characterized one. |
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TNN Polyclonal Antibody |
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| RD76582A-20uL | Reddot Biotech | 20μL | 109.5 EUR |
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Description: This protein is involved in neurite outgrowth and cell migration in hippocampal explants.It has three EGF-like domains, one fibrinogen C-terminal domain and nine fibronectin type III domains.Tenascins are extracellular matrix proteins present during the development of organisms as well as in pathological conditions.Tenascin-W, the fourth and last member of the tenascin family remains the least well-characterized one. |
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TNN Polyclonal Antibody |
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| RD76582A-60uL | Reddot Biotech | 60μL | 214.5 EUR |
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Description: This protein is involved in neurite outgrowth and cell migration in hippocampal explants.It has three EGF-like domains, one fibrinogen C-terminal domain and nine fibronectin type III domains.Tenascins are extracellular matrix proteins present during the development of organisms as well as in pathological conditions.Tenascin-W, the fourth and last member of the tenascin family remains the least well-characterized one. |
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Anti-TENN TNN Antibody |
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| A05722 | BosterBio | 100ul | 380 EUR |
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Description: Boster Bio Anti-TENN TNN Antibody catalog # A05722. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. |
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Tenascin-N (TNN) Antibody |
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| abx027503-400l | Abbexa | 400 µl | 518.75 EUR |
Tenascin-N (TNN) Antibody |
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| abx027503-400ul | Abbexa | 400 ul | 627.6 EUR |
Tenascin-N (TNN) Antibody |
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| abx027503-80l | Abbexa | 80 µl | 250 EUR |
Tenascin-N (TNN) Antibody |
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| abx213586-100g | Abbexa | 100 µg | 250 EUR |
Tenascin-N (TNN) Antibody |
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| 20-abx213586 | Abbexa |
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Tenascin-N (TNN) Antibody |
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| abx213587-100g | Abbexa | 100 µg | 250 EUR |
Tenascin-N (TNN) Antibody |
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| 20-abx213587 | Abbexa |
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Tenascin-N (TNN) Antibody |
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| abx349685-96tests | Abbexa | 96 tests | 162.5 EUR |
TNN Antibody, HRP conjugated |
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| 1-CSB-PA892498LB01HU | Cusabio |
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Description: A polyclonal antibody against TNN. Recognizes TNN from Human. This antibody is HRP conjugated. Tested in the following application: ELISA |
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TNN Antibody, HRP conjugated |
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| MBS7110556-005mg | MyBiosource | 0.05mg | 190 EUR |
TNN Antibody, HRP conjugated |
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| MBS7110556-01mg | MyBiosource | 0.1mg | 270 EUR |
TNN Antibody, HRP conjugated |
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| MBS7110556-5x01mg | MyBiosource | 5×0.1mg | 1205 EUR |
TNN Antibody, FITC conjugated |
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| 1-CSB-PA892498LC01HU | Cusabio |
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Description: A polyclonal antibody against TNN. Recognizes TNN from Human. This antibody is FITC conjugated. Tested in the following application: ELISA |
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TNN Antibody, FITC conjugated |
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| MBS7110557-005mg | MyBiosource | 0.05mg | 190 EUR |
TNN Antibody, FITC conjugated |
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| MBS7110557-01mg | MyBiosource | 0.1mg | 270 EUR |
TNN Antibody, FITC conjugated |
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| MBS7110557-5x01mg | MyBiosource | 5×0.1mg | 1205 EUR |
TNN Antibody, Biotin conjugated |
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| 1-CSB-PA892498LD01HU | Cusabio |
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Description: A polyclonal antibody against TNN. Recognizes TNN from Human. This antibody is Biotin conjugated. Tested in the following application: ELISA |
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TNN Antibody, Biotin conjugated |
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| MBS7110558-005mg | MyBiosource | 0.05mg | 190 EUR |
TNN Antibody, Biotin conjugated |
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| MBS7110558-01mg | MyBiosource | 0.1mg | 270 EUR |
TNN Antibody, Biotin conjugated |
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| MBS7110558-5x01mg | MyBiosource | 5×0.1mg | 1205 EUR |
Tenascin-N (TNN) Antibody (HRP) |
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| abx349686-96tests | Abbexa | 96 tests | 162.5 EUR |
Tenascin-N (TNN) Antibody (FITC) |
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| abx349687-96tests | Abbexa | 96 tests | 162.5 EUR |
Tenascin-N (TNN) Antibody (Biotin) |
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| abx349688-96tests | Abbexa | 96 tests | 162.5 EUR |
TNN antibody – N-terminal region |
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| MBS3215924-01mL | MyBiosource | 0.1mL | 455 EUR |
TNN antibody – N-terminal region |
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| MBS3215924-5x01mL | MyBiosource | 5×0.1mL | 1995 EUR |
TNN Rabbit Polyclonal Antibody |
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| E10G04486 | EnoGene | 100 μl | 275 EUR |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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TNN Rabbit Polyclonal Antibody |
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| E10G11376 | EnoGene | 100 μl | 275 EUR |
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Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody |
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TNN Antibody (Center) Blocking peptide |
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| MBS9220054-INQUIRE | MyBiosource | INQUIRE | Ask for price |
Polyclonal TNN antibody – N-terminal region |
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| AMM08262G | Leading Biology | 0.05mg | 633.6 EUR |
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Description: A polyclonal antibody raised in Rabbit that recognizes and binds to Human TNN – N-terminal region. This antibody is tested and proven to work in the following applications: |
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OAAB09919-400UL – TNN Antibody – middle region |
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| OAAB09919-400UL | Aviva Systems Biology | 400ul | 389 EUR |
Anti-Human TNN/Tenascin-N Antibody |
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| MBS1569297-01mg | MyBiosource | 0.1mg | 405 EUR |
Anti-Human TNN/Tenascin-N Antibody |
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| MBS1569297-5x01mg | MyBiosource | 5×0.1mg | 1520 EUR |
ARP63200_P050-25UL – TNN Antibody – N-terminal region |
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| ARP63200_P050-25UL | Aviva Systems Biology | 25ul | 99 EUR |
ARP63200_P050 – TNN antibody – N-terminal region (ARP63200_P050) |
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| ARP63200_P050 | Aviva Systems Biology | 100ul | 389 EUR |
TNN, ID (TNN, Tenascin-N) |
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| MBS6010844-02mL | MyBiosource | 0.2(mL | 695 EUR |
TNN, ID (TNN, Tenascin-N) |
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| MBS6010844-5x02mL | MyBiosource | 5×0.2mL | 2975 EUR |
TNN, ID (TNN, Tenascin-N) (AP) |
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| MBS6357197-02mL | MyBiosource | 0.2mL | 980 EUR |
TNN, ID (TNN, Tenascin-N) (AP) |
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| MBS6357197-5x02mL | MyBiosource | 5×0.2mL | 4250 EUR |
TNN, ID (TNN, Tenascin-N) (PE) |
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| MBS6357207-02mL | MyBiosource | 0.2mL | 980 EUR |
TNN, ID (TNN, Tenascin-N) (PE) |
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| MBS6357207-5x02mL | MyBiosource | 5×0.2mL | 4250 EUR |
TNN, ID (TNN, Tenascin-N) (APC) |
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| MBS6357198-02mL | MyBiosource | 0.2mL | 980 EUR |
TNN, ID (TNN, Tenascin-N) (APC) |
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| MBS6357198-5x02mL | MyBiosource | 5×0.2mL | 4250 EUR |
TNN, ID (TNN, Tenascin-N) (FITC) |
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| MBS6357200-02mL | MyBiosource | 0.2mL | 980 EUR |
TNN, ID (TNN, Tenascin-N) (FITC) |
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| MBS6357200-5x02mL | MyBiosource | 5×0.2mL | 4250 EUR |
TNN, ID (TNN, Tenascin-N) (Biotin) |
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| MBS6357199-02mL | MyBiosource | 0.2mL | 980 EUR |
TNN, ID (TNN, Tenascin-N) (Biotin) |
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| MBS6357199-5x02mL | MyBiosource | 5×0.2mL | 4250 EUR |
TNN (untagged)-Human tenascin N (TNN) |
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| SC304989 | Origene Technologies GmbH | 10 µg | Ask for price |
TNN, ID (TNN, Tenascin-N) (MaxLight 405) |
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| MBS6357202-01mL | MyBiosource | 0.1mL | 980 EUR |
TNN, ID (TNN, Tenascin-N) (MaxLight 405) |
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| MBS6357202-5x01mL | MyBiosource | 5×0.1mL | 4250 EUR |
TNN, ID (TNN, Tenascin-N) (MaxLight 490) |
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| MBS6357203-01mL | MyBiosource | 0.1mL | 980 EUR |
TNN, ID (TNN, Tenascin-N) (MaxLight 490) |
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| MBS6357203-5x01mL | MyBiosource | 5×0.1mL | 4250 EUR |
TNN, ID (TNN, Tenascin-N) (MaxLight 550) |
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| MBS6357204-01mL | MyBiosource | 0.1mL | 980 EUR |
TNN, ID (TNN, Tenascin-N) (MaxLight 550) |
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| MBS6357204-5x01mL | MyBiosource | 5×0.1mL | 4250 EUR |
TNN, ID (TNN, Tenascin-N) (MaxLight 650) |
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| MBS6357205-01mL | MyBiosource | 0.1mL | 980 EUR |
TNN, ID (TNN, Tenascin-N) (MaxLight 650) |
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| MBS6357205-5x01mL | MyBiosource | 5×0.1mL | 4250 EUR |
TNN, ID (TNN, Tenascin-N) (MaxLight 750) |
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| MBS6357206-01mL | MyBiosource | 0.1mL | 980 EUR |
TNN, ID (TNN, Tenascin-N) (MaxLight 750) |
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| MBS6357206-5x01mL | MyBiosource | 5×0.1mL | 4250 EUR |
Tnn (untagged) – Mouse tenascin N (Tnn), (10ug) |
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| MC224688 | Origene Technologies GmbH | 10 µg | Ask for price |
Anti-TNN Antibody, Rabbit Polyclonal |
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| MBS8109289-01mL | MyBiosource | 0.1mL | 300 EUR |
Anti-TNN Antibody, Rabbit Polyclonal |
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| MBS8109289-5x01mL | MyBiosource | 5×0.1mL | 1200 EUR |
Anti-TNN Rabbit Polyclonal Antibody |
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| TA322208 | Origene Technologies GmbH | 100 µl | Ask for price |
Anti-TNN Rabbit Polyclonal Antibody |
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| TA322209 | Origene Technologies GmbH | 100 µl | Ask for price |
TNN, ID (TNN, Tenascin-N) (Azide free) (HRP) |
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| MBS6357201-02mL | MyBiosource | 0.2mL | 980 EUR |
TNN, ID (TNN, Tenascin-N) (Azide free) (HRP) |
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| MBS6357201-5x02mL | MyBiosource | 5×0.2mL | 4250 EUR |
Tnn (untagged ORF) – Rat tenascin N (Tnn), (10 ug) |
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| RN201535 | Origene Technologies GmbH | 10 µg | Ask for price |
Mouse TNN siRNA |
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| 20-abx937676 | Abbexa |
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Human TNN siRNA |
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| 20-abx937677 | Abbexa |
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TNN siRNA (Human) |
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| MBS8223702-15nmol | MyBiosource | 15nmol | 405 EUR |
TNN siRNA (Human) |
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| MBS8223702-30nmol | MyBiosource | 30nmol | 565 EUR |
