The China tuberculosis clinical trials consortium network: a model for international TB clinical trials capacity building.

With the second largest tuberculosis (TB) burden globally, China is committed to actively engage in international TB clinical trials to contribute to global TB research. However, lack of research capacity among local sites has been identified as a barrier.

The China Tuberculosis Clinical Trials Consortium (CTCTC) was initiated by Beijing Chest Hospital with investment from the US National Institutes of Health and technical support from Family Health International 360 in 2013, as a nationwide collaborative clinical trial network to strengthen selected clinical site research capacity and attract TB clinical trials.

The program aims to: 1) recruit leading hospitals that care for TB patients; 2) conduct on-site assessment to identify capacity gaps and needs for improvement; 3) design and deliver capacity building activities; 4) attract and deliver high quality results for TB clinical trials.

A total of 24 sites have joined CTCTC, covering 20 provinces in China. Twenty-two sites have been accredited by the National Medical Products Administration (NMPA) to be qualified to conduct TB clinical trials. The onsite assessment, extensive trainings among the CTCTC sites and young investigators have resulted in better understanding and improvement of the site capacity in conducting TB clinical trials.

The establishment and growth of the CTCTC network has benefited from the good leadership, effective international cooperation and local commitment.

FluoroQuest™ Anti-fading Kit II *Optimized for Plate Imaging*
20003 1 kit
EUR 132
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Hamster IgG-Biotin conjugate, isotype control (Syrian)
20003-1-B 100 test
EUR 164

Hamster IgG, purified (Armenian, Isotype control)
20003-1AH 1 mg
EUR 263

G. Pig IgG Fc-Biotin conjugate (isotype control, non-immune) purified
20004-3-B 0.1 mg
EUR 225

G. Pig IgG-Biotin conjugate (isotype control)
20004-B 100 ug
EUR 202

Rat IgG F(ab')2 fragment, purified (isotype control)
20005-1-FAB2 1 mg
EUR 202

Rat IgG (Fc)-Biotin Conjuagte (isotype control), purified
20005-1-FC-B 0.1 mg
EUR 225

Rat IgG1-Biotin conjugate (isotype control)
20005-11-B 100 ug
EUR 202

Rat IgG2a-APC conjugate (isotype control)
20005-12-APC 25 tests
EUR 202

Rat IgG2a-Biotin conjugate (isotype control)
20005-12-B 100 ug
EUR 202

Rat IgG2b-Biotin conjugate (isotype control)
20005-13-B 100 ug
EUR 202

Rat IgG2c-Biotin conjugate (isotype control)
20005-14-B 100 ug
EUR 225

Rat IgM-Biotin conjugate (isotype control)
20005-21-B 100 ug
EUR 225

Rat IgG-Agarose conjugate(aff matrix)
20005-AS-1 0.5 ml
EUR 164

Rat IgG-Biotin conjugate (isotype control) (Isotype control)
20005-B 100 ug
EUR 164

Sheep IgG-Biotin Conjugate (isotype control, non-immune), purified
20006-1-B 0.5 mg
EUR 202

Sheep IgM-Biotin Conjugate (non-immune) control, purified
20006-2-B 0.1 mg
EUR 225

Sheep IgG Fc-Biotin Conjugate (isotype control, non-immune), purified
20006-4-B 0.5 mg
EUR 202

Human IgG-Biotin conjugate (isotype control, non-immune), purified
20007-1-B 0.5 mg
EUR 225

Human IgG (>98%, non-immune, control, Liquid @ 10 mg/ml, azide free, bulk size)
20007-1-BL-1 10 ml Ask for price

Human IgG (>98%, non-immune, control, powder, azide free, bulk size)
20007-1-BP-1 1 g
EUR 651

Human IgG (>98%, non-immune, control, powder, azide free, bulk size)
20007-1-BP-10 10 g
EUR 4313

Human IgG Fab fragment-Biotin Conjugate, purified
20007-1-FAB-B 0.1 mg
EUR 202

Human IgG F(ab')2 fragment, purified
20007-1-FAB2 1 mg
EUR 202

Human IgG Fab2 fragment-Biotin Conjugate, purified
20007-1-FAB2-B 0.1 mg
EUR 202

Human IgG Fc-Biotin conjugate (isotype control, non-immune), purified
20007-1-Fc-B 0.1 mg
EUR 164

Human IgG (Fc) fragment, purified (>95%, low endotoxin)
20007-1-FC-LE 100 ul
EUR 225

Human IgG (Fc) fragment-Biotin purified (>95%, low endotoxin)
20007-1-FC-LE-B 25 ug
EUR 286

Human IgG (serum origin, purified >97%, low endotoxin, azide free)
20007-1-LE-1 1 mg
EUR 164

Human IgG-Biotin (serum origin, purified >97%, low endotoxin, azide free)
20007-1-LE-BTN 100 ug
EUR 286

TruStrip RDT Human IgG Rapid test cards, 10/pk
20007-1-RDT 1 Pk
EUR 171

TruStrip RDT Human IgG Rapid test cards, 25/pk
20007-1-RDT-25 1 Pk
EUR 293

Human IgM, purified (native, isotype control, >96% pure, ELISA Grade)
20007-2 1 mg
EUR 164

Human IgM purified (isotype control, >96% pure, ELISA Grade)
20007-2-10 10 mg
EUR 895

Human IgM purified (isotype control, >96% pure, ELISA Grade)
20007-2-5 5 mg
EUR 529

Human IgM (myeloma, >96%, non-immune, control; bulk size)
20007-2-B-100 100 mg Ask for price

Human IgM (myeloma, >96%, non-immune, control; bulk size)
20007-2-B-1000 1000 mg Ask for price

Human IgM-Biotin conjugate (myeloma, isotype control)
20007-2-MB 100 ug
EUR 164

Human IgM (Rheumatoid Factor plasma, >40,000 IU/ml, purifed for ELISA)
20007-2-RF 100 ul
EUR 469

Human IgE (myeloma, kappa), purified (isotype control, >95%, low endotoxin, azide free)
20007-3-LE-50 100 ug
EUR 408

Human IgE-Biotin (myeloma, kappa), purified (isotype control, >95%, low endotoxin, azide free)
20007-3-LE-BTN 100 ul
EUR 408

Human IgM Fab mu fragment (myeloma)-Biotin conjugate (isotype control)
20007-4-B 100 ug
EUR 225

Human IgG-Fc fragment (97%, low endotoxin, azide free)
20007-F-LE-100 100 ug
EUR 164

Human IgG-Fc fragment-Biotin (97%, low endotoxin, azide free)
20007-F-LE-BTN 100 ug
EUR 286

Human IgG1-Biotin Conjugate (-ve control)
20007-G1-B 100 ug
EUR 164

Recombinant (HEK) Human IgG1 Fc (103Cys/Ser, 99-330aa, His-tag, >95%, low endotoxin)
20007-G1-FC 50 ug
EUR 286

Human IgG2-Biotin Conjugate
20007-G2-B 100 ug
EUR 164

Recombinant (HEK) Human IgG2-Fc (257Ser/Ala, 99-327aa, His-tag, >95%, low endotoxin)
20007-G2-FC 50 ug
EUR 286

Human IgG3-Biotin Conjugate
20007-G3-B 100 ug
EUR 164

Recombinant (HEK) Human IgG3-Fc (99-377aa, His-tag, >95%, low endotoxin)
20007-G3-FC 50 ug
EUR 286

Human IgG4-Biotin Conjugate
20007-G4-B 100 ug
EUR 164

Recombinant (HEK) Human IgG4-Fc (108Ser/Pro, 99-327aa, His-tag, >95%, low endotoxin)
20007-G4-FC 50 ug
EUR 286

Mouse IgG F(ab')2 fragment, purified
20008-1-Fab2 1 mg
EUR 202

Mouse IgG (>97%, ELISA/RIA/Diagnostic Grade; -ve mouse viruses & Protein A/G free)
20008-1-WA 1 mg
EUR 164

Mouse IgG-Agarose conjugate (aff matrix)
20008-AS-1 0.5 ml
EUR 164

Mouse IgG-Biotin conjugate (isotype control)
20008-B 50 Tests
EUR 164

Mouse IgG-Biotin conjugate (isotype control)
20008-BT-1 1 mg
EUR 164

Mouse IgG Fab-Biotin conjugate (isotype control)
20008-Fab-B 100 ug
EUR 164

Mouse IgG F(ab')2-Biotin conjugate (isotype control)
20008-Fab2-B 100 ug
EUR 164

Mouse IgG F(ab')2-FITC conjugate (isotype control)
20008-Fab2-F 100 ug
EUR 164

Mouse IgG F(ab')2-HRP conjugate (isotype control)
20008-Fab2-HP 100 ug
EUR 164

Mouse IgG F(c)-Biotin conjugate (isotype control)
20008-Fc-B 100 ug
EUR 164

Rabbit IgG Fab-Biotin Conjugate, purified
20009-1-FAB-B 0.1 mg
EUR 202

Rabbit IgG F(ab')2 fragment, purified
20009-1-FAB2 1 mg
EUR 202

Recombinant (HEK) Rabbit IgG (Fc) (101-323aa, 185Thr/Asn284Ser, ~33 kda, >95%, Low Endotoxin)
20009-1-R-FC 50 ug
EUR 286

Rabbit IgM-Biotin Conjugate (isotype control, non-immune), purified
20009-2-1-B 0.1 mg
EUR 225

Rabbit IgA-Biotin Conjugate (isotype control, non-immune), purified
20009-3-1-B 0.1 mg
EUR 408

Rabbit IgG-Agarose conjugate
20009-AS-1 0.5 ml
EUR 164

Rabbit IgG (Whole, non-immune)-Biotin conjugate
20009-B 100 ug
EUR 164

Rabbit IgG-biotinylated (isotype control)
20009-BT-1 1 mg
EUR 286

Rabbit IgG F(ab')2-biotin conjugate, isotype control
20009-FAb2-B 100 ug
EUR 164

Rabbit IgG F(ab')2-FITC conjugate, isotype control
20009-FAb2-F 100 ug
EUR 164

Rabbit IgG F(ab')2-HRP conjugate, isotype control
20009-FAb2-HP 100 ug
EUR 164

Rabbit IgG F(ab')2-R-PE conjugate, isotype control
20009-FAb2-PE 100 tests
EUR 225

Rabbit IgG F(c)-biotin conjugate, isotype control
20009-Fc-B 100 ug
EUR 164

Rabbit IgG, purified (serum non-immune, isotype control), without azide, powder
20009-WA-1 1 mg
EUR 141

Rabbit IgG, purified (serum non-immune, isotype control), without azide, powder
20009-WA-5 5 mg
EUR 286

Human Insulin Antibody
20010-05011 150 ug
EUR 217

Human Insulin Antibody (Biotin Conjugate)
20010-05021 150 ug
EUR 276

Chicken IgG-Biotin conjugate (isotype control, non-immune), purified
20010-1-B 0.5 mg
EUR 225

Chicken IgM-Biotin conjugate (isotype control, non-immune) purified
20010-2-1-b 0.1 mg
EUR 225

Chicken IgG-Fc-Biotin conjugate (isotype control, non-immune), purified
20010-3-B 0.1 mg
EUR 225

Human Synaptobrevin-2 Antibody
20011-05011 150 ug
EUR 217

Human Synaptobrevin-2 Antibody (Biotin Conjugate)
20011-05021 150 ug
EUR 276

Human Synaptobrevin-2 AssayLite Antibody (FITC Conjugate)
20011-05041 150 ug
EUR 428

Human Synaptobrevin-2 AssayLite Antibody (RPE Conjugate)
20011-05051 150 ug
EUR 428

Human Synaptobrevin-2 AssayLite Antibody (APC Conjugate)
20011-05061 150 ug
EUR 428

Human Synaptobrevin-2 AssayLite Antibody (PerCP Conjugate)
20011-05071 150 ug
EUR 471

Goat IgG FAB fragment-Biotin conjugate
20011-1-FAB-B 100 tests
EUR 225

Goat IgG F(ab')2 fragment, purified
20011-1-FAB2 1 mg
EUR 164

Goat IgG-Agarose conjugate(aff matrix)
20011-AS-1 0.5 ml
EUR 164

Goat IgG (Whole, non-immune)-Biotin conjugate
20011-B 100 ug
EUR 164

Goat IgG F(ab')2 fragment-Biotin conjugate
20011-FAB2-B 100 tests
EUR 202

Goat IgG F(ab')2 fragment-Cy5 conjugate
20011-FAB2-Cy5 50 tests
EUR 202

Goat IgG F(ab')2 fragment-FITC conjugate
20011-FAB2-F 100 tests
EUR 202

Goat IgG FAB(ab')2 fragment-HRP conjugate
20011-FAB2-HP 100 tests
EUR 202

Goat IgG F(ab')2 fragment-R-PE conjugate
20011-FAB2-PE 50 tests
EUR 202

Goat IgG (fc)-Biotin conjugate (isotype control)
20011-Fc-B 100 ug
EUR 164

E. coli GroEL Antibody
20012-05011 150 ug
EUR 217

E. coli GroEL Antibody (Biotin Conjugate)
20012-05021 150 ug
EUR 276

E. coli GroEL AssayLite Antibody (FITC Conjugate)
20012-05041 150 ug
EUR 428

E. coli GroEL AssayLite Antibody (RPE Conjugate)
20012-05051 150 ug
EUR 428

E. coli GroEL AssayLite Antibody (APC Conjugate)
20012-05061 150 ug
EUR 428

E. coli GroEL AssayLite Antibody (PerCP Conjugate)
20012-05071 150 ug
EUR 471

Monkey IgG (Rhesus, Whole, non-immune)-Biotin conjugate
20012-B 100 ug
EUR 202

Chimpanzee IgG (non-immune)-Biotin conjugate
20012-Ch-B 100 ug
EUR 286

CF488A F(ab')2 fragment of goat anti-rabbit IgG(H+L), 2 mg/mL
20013 0.25 mL
EUR 190
Description: Minimum order quantity: 1 unit of 0.25 mL

Human Interferon-gamma (IFN-gamma) Antibody
20013-05011 150 ug
EUR 217

Human Interferon-gamma (IFN-gamma) Antibody (Biotin Conjugate)
20013-05021 150 ug
EUR 276

Human Interferon-gamma (IFN-gamma) AssayLite Antibody (FITC Conjugate)
20013-05041 150 ug
EUR 428

Human Interferon-gamma (IFN-gamma) AssayLite Antibody (RPE Conjugate)
20013-05051 150 ug
EUR 428

Human Interferon-gamma (IFN-gamma) AssayLite Antibody (APC Conjugate)
20013-05061 150 ug
EUR 428

Human Interferon-gamma (IFN-gamma) AssayLite Antibody (PerCP Conjugate)
20013-05071 150 ug
EUR 471

Monkey Serum IgM-biotin conjugate (Rhesus, non-immune, isotype control), purified
20013-1-B 25 ug
EUR 225

Annexin V, Recombinant
20014 100 ug
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Annexin V, Recombinant
20015 1 mg
EUR 702
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Donkey IgG-Biotin conjugate (non-immune, isotype control) purified
20015-1-B 0.5 mg
EUR 225

Donkey IgM-Biotin conjugate (unlabeled, non-immune, isotype control) purified
20015-2-1-B 0.1 mg
EUR 225

Donkey IgG (Whole, non-immune)-Biotin conjugate
20015-B 100 ug
EUR 164

Dog IgG-Biotin Conjugate (isotype control, non-immune), purified
20016-1-B 0.1 mg
EUR 225

Dog IgG F(ab')2 fragment (isotype control, non-immune) purified
20016-1-FAB2 1 mg
EUR 164

Dog IgG Fc-Biotin Conjugate (isotype control, non-immune), purified
20016-FC-B 0.1 mg
EUR 225

Pig IgG-Biotin conjugate (swine non-immune, isotype control), purified
20017-1-B 0.1 mg
EUR 263

Pig IgM-Biotin (swine non-immune, isotype control), purified
20017-2-1-B 0.1 mg
EUR 263

Pig IgG Fc-Biotin conjugate (swine non-immune, isotype control), purified
20017-3-B 0.1 mg
EUR 263

Monkey Serum IgM-biotin conjugate (Cyno., non-immune, isotype control), purified
20018-1-B 100 ug
EUR 263

Monkey IgG (Cynomolgous, non-immune)-Biotin conjugate
20018-B 100 ug
EUR 202

Goat Anti-Rabbit IgA (alpha chain) unlabeled, aff pure
20019 0.5 mg
EUR 202

Horse IgM (Equine, Whole IgM, control, non-immune)-biotinylated, purified
20019-2-B 100 ug
EUR 202

Horse IgG (Equine, Whole IgG, control, non-immune)-biotinylated, purified
20019-B 0.5 mg
EUR 164

Bison IgG, semi-pure for ELISA (Control, non-immune, isotype control)
20025-1 100 ug
EUR 225

Goat Anti-Rabbit IgA (alpha chain)-HRP conjugate
20029 0.5 ml
EUR 263

Annexin V, FITC Labeled
20030 100 tests
EUR 219
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

TruStrip RDT Llama IgG Rapid test cards, 10/pk
20030-RDT-10 1 Pk
EUR 171

TruStrip RDT Llama IgG Rapid test cards, 25/pk
20030-RDT-25 1 Pk
EUR 293

Alpaca IgG (Control, non-immune, isotype control, ELISA grade)
20032-1 1 mg
EUR 164

CF555 goat anti-rabbit IgG(H+L), 2mg/mL
20033-1 50uL
EUR 120
Description: Minimum order quantity: 1 unit of 50uL

CF555 goat anti-chicken IgY (IgG) (H+L), highly cross-adsorbed, 2 mg/mL
20034-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF555 F(ab')2 fragment of goat anti-rabbit IgG(H+L), 2 mg/mL
20035 0.25 mL
EUR 190
Description: Minimum order quantity: 1 unit of 0.25 mL

CF555 F(ab')2 fragment of goat anti-rabbit IgG(H+L), 2 mg/mL
20035-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF555 goat anti-guinea pig IgG(H+L), 2 mg/mL
20036-1 50uL
EUR 120
Description: Minimum order quantity: 1 unit of 50uL

CF555 donkey anti-mouse IgG(H+L), highly cross-adsorbed, 2 mg/mL
20037-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF555 donkey anti-rabbit IgG(H+L), highly cross-adsorbed, 2 mg/mL
20038-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF555 donkey anti-goat IgG(H+L), highly cross-adsorbed, 2 mg/mL
20039-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

DABCYL succinimidyl ester [4-((4-(Dimethylamino)phenyl)azo)benzoic acid, succinimidyl ester] *CAS 146998-31-4*
2004 1 g
EUR 350
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

CF647 goat anti-mouse IgG(H+L), 2mg/mL
20040-1 50uL
EUR 120
Description: Minimum order quantity: 1 unit of 50uL

CF647 goat anti-guinea pig IgG(H+L), 2 mg/mL
20041-1 50uL
EUR 120
Description: Minimum order quantity: 1 unit of 50uL

CF647 F(ab')2 fragment of goat anti-mouse IgG(H+L), 2 mg/mL
20042-1 50ul
EUR 137
Description: Minimum order quantity: 1 unit of 50ul

CF647 goat anti-rabbit IgG(H+L), 2mg/mL
20043-1 50uL
EUR 120
Description: Minimum order quantity: 1 unit of 50uL

CF647 goat anti-chicken IgY (IgG) (H+L), highly cross-adsorbed, 2 mg/mL
20044-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF647 F(ab')2 fragment of goat anti-rabbit IgG(H+L), 2 mg/mL
20045 0.25mL
EUR 190
Description: Minimum order quantity: 1 unit of 0.25mL

CF647 F(ab')2 fragment of goat anti-rabbit IgG(H+L), 2 mg/mL
20045-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF647 donkey anti-mouse IgG(H+L), highly cross-adsorbed, 2 mg/mL
20046-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF647 donkey anti-rabbit IgG(H+L), highly cross-adsorbed, 2mg/mL
20047-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF647 donkey anti-goat IgG(H+L), highly cross-adsorbed, 2 mg/mL
20048-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF647 rabbit anti-goat IgG(H+L), 2 mg/mL
20049-1 50uL
EUR 120
Description: Minimum order quantity: 1 unit of 50uL

DABCYL succinimidyl ester [4-((4-(Dimethylamino)phenyl)azo)benzoic acid, succinimidyl ester] *CAS 146998-31-4*
2005 5 g
EUR 1311
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

Pluronic® F-127 *Cell culture tested *
20050 10 g
EUR 115
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

CF660C goat anti-mouse IgG(H+L), 2 mg/mL
20050-1 50uL
EUR 120
Description: Minimum order quantity: 1 unit of 50uL

CF660C donkey anti-goat IgG(H+L), highly cross-adsorbed, 2 mg/mL
20051-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF660C goat anti-mouse IgG(H+L), highly cross-adsorbed, 2 mg/mL
20052-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

Pluronic® F-127 *10% solution in water*
20053 10 mL
EUR 115
  • R-phrase: R20, R21, R22
  • H-Phrase: H303, H313, H333
  • Symbol for dangerous compounds: Xn
  • UNSPEC Code: 12352200

CF660C goat anti-rabbit IgG(H+L), 2 mg/mL
20053-1 50uL
EUR 120
Description: Minimum order quantity: 1 unit of 50uL

CF660R goat anti-mouse IgG(H+L), 2 mg/mL
20054-1 50uL
EUR 120
Description: Minimum order quantity: 1 unit of 50uL

CF660R goat anti-rabbit IgG(H+L), 2 mg/mL
20055-1 50uL
EUR 120
Description: Minimum order quantity: 1 unit of 50uL

CF680 donkey anti-goat IgG(H+L), highly cross-adsorbed, 2 mg/mL
20060 0.25mL
EUR 255
Description: Minimum order quantity: 1 unit of 0.25mL

CF680 donkey anti-goat IgG(H+L), highly cross-adsorbed, 2 mg/mL
20060-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF680 rabbit anti-mouse IgG(H+L), highly cross-adsorbed, 2 mg/mL
20061-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF680 donkey anti-sheep IgG(H+L), highly cross-adsorbed, 2 mg/mL
20062-1 50uL
EUR 137
Description: Minimum order quantity: 1 unit of 50uL

CF680 F(ab')2 fragment of goat anti-mouse IgG(H+L), 2 mg/mL
20063 0.25mL
EUR 219
Description: Minimum order quantity: 1 unit of 0.25mL

Issues in human resources, regulatory environment and sustainability have been challenging the network from continuing growth. Clinical researchers have full-time clinical responsibilities in China and it is thus important to build a cadre of other human resources to assist. The regulatory environment is becoming friendlier in China to introduce international clinical trials to the CTCTC network.The CTCTC, with mature management structure and sustainable development model, which are distilled five key lessons for other developing countries or investigators of interest. They are the respectively using assessment-based approach to design tailored training package, understanding the availability of clinical researchers, providing solutions to maintain sustainability, understanding local regulatory environments and working with an international organization with local on-site team, respectively. Although, the experiences and capacity of China’s TB hospitals in conducting clinical research vary. Considerable efforts to continue building the capacity are still needed, although the gap is smaller for a few top-tier hospitals.